Long-term effects of repeated pregnancies (multiparity) on blood pressure regulation

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Long-term effects of repeated pregnancies (multiparity) on blood pressure regulation.

OBJECTIVE Pregnancy is associated with profound alterations in the cardiovascular system, the long-term effects of which are unknown. Human epidemiological studies suggest that multiparity (multiple pregnancies) increases the risk of cardiovascular disease. The mechanisms underlying these findings remain to be elucidated. The objective of this study was to determine the long-term effects of par...

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Introduction: Kidney transplantation from a live donor has many advantages, but the donor should undergo a major surgery and accept potential morbidity and mortality. In this study, we evaluated the long term effects of nephrectomy on renal function and blood pressure of kidney donors. Methods: In this cross-sectional study, we assessed 195 kidney donors. The controls were 100 healthy individu...

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Repeated pregnancies (multiparity) increases venous tone and reduces compliance.

In humans, multiparity (repeated pregnancy) is associated with increased risk of cardiovascular disease. In rats, multiparity increases the pressor response to phenylephrine and to acute stress, due in part to changes in tone of the splanchnic arterial vasculature. Given that the venous system also changes during pregnancy, we studied the effects of multiparity on venous tone and compliance. Ca...

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Effect of multiparity on electrolyte composition and blood pressure.

Pregnancy affects the physiology of the pregnant woman particularly the endocrine, cardiovascular and the renal systems. This work was therefore set to ascertain the state of electrolytes in pregnancy and how it affects blood pressure using multiparity as a factor. One hundred and twenty (120) women were used in this study. The non-pregnant groups were the nulliparous (control) and grand multip...

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ژورنال

عنوان ژورنال: Cardiovascular Research

سال: 2004

ISSN: 0008-6363

DOI: 10.1016/j.cardiores.2004.06.018